Colorado Center for Reproductive Medicine

2009 Statistics

The Colorado Center for Reproductive Medicine (CCRM) is pleased to announce our 2009 SART IVF success rate data along with our increased take home baby rates per embryo transfer for all age groups from age 35 to 44 years undergoing Comprehensive Chromosome Screening (CCS). What is particularly worth noting is the increase in the 41-42 year old women with CCS. In 2008, 30.9% of embryo transfers from fresh cycles resulted in a take home baby for 41 to 42 year olds, and in 2009, 46.2% of frozen embryo transfers following CCS testing resulted in a take home baby for this age group. With CCRM’s latest addition of comprehensive chromosome screening our fertility success rates continue to be among the highest in the nation.

Towards the bottom of this page is the CCRM 2009 Clinic Summary Report which was submitted to and now published by the Society for Assisted Reproductive Technology (SART). SART does not include any planned freeze all cycles in its summary of “Fresh Embryos from Non-Donor Oocytes” which means CCRM’s egg retrievals for Comprehensive Chromosome Screening (CCS) are not included in the 2009 SART published data below.

The following unpublished (by SART) CCS statistics are provided for patients who are interested in CCRM’s 2009 IVF success rates with this technology. In 2009, the Colorado Center for Reproductive Medicine did 285 egg retrievals on patients planning to have an “embryo freeze all” cycle as the patients were having their embryos tested for 23 pairs of chromosomes through Comprehensive Chromosome Screening (CCS) technology. Upon completion of the CCS testing, CCRM did 138 frozen embryo transfers for CCS patients with chromosomally normal embryos. Some patients having egg retrievals with CCS in 2009 will not have their frozen embryo transfers until 2010. The following is the data for fertility success rates from the 2009 CCS transfer patients:

2009 Data -- Thawed Embryos from CCS Testing Patients

	2009 CCS Frozen Embryo Transfer Statistics Comprehensive Chromosome Screening Age
	<35	35-37	38-40	41-42	43-44
Number of transfers	26	30	49	26	7
Percentage of transfers resulting in pregnancies (FHT)	69.2	66.7	59.2	50	1/7
Percentage of transfers resulting in live births	69.2	66.7	59.2	46.2	1/7
Percent with single embryo transfer	11.5	26.7	34.7	46.2	0
Implantation Rate	52.9	48.2	50	44.4	2/12
Average number of embryos transferred	1.96	1.87	1.76	1.73	1.71
Percentage of live births with twins	44.4	35	41.4	30.8	100
Percentage of live births with triplets or more	0	0	0	3.8	0

SART Data

Fresh Embryos from Non-donor Eggs

	Age of Woman
	<35	35-37	38-40	41-42	>42
Number of cycles	192	134	131	56	68
Percentage of cycles resulting in pregnancies ^c	68.8	59.0	51.1	25.0	20.6
Percentage of cycles resulting in live births ^b,c	63.0	53.0	42.0	14.3	7.4
(Reliability Range)	(56.2-69.8)	(44.5-61.4)	(33.5-50.4)	(5.1-23.5)	(1.1-13.6)
Percentage of retrievals resulting in live births ^b,c	66.1	55.9	43.5	15.4	7.4
Percentage of transfers resulting in live births ^b,c	68.0	58.2	44.4	17.0	7.8
Percentage of transfers with elective single embryo transfer	6.2	2.5	0.8	0	1.6
Percentage of cancellations ^c	4.7	5.2	3.8	7.1	0
Implantation rate	51.8	38.4	21.7	9.0	3.6
Average number of embryos transferred	2.2	2.4	3.0	4	3.9
Percentages of live births with twins ^c	38.8	28.2	9.1	3/8	0/5
Percentage of live births with triplets or more ^c	1.7	2.8	3.6	0/8	0/5

Frozen Embryos from Non-donor Eggs

	Age of Woman
	<35	35-37	38-40	41-42	>42
Number of transfers	109	106	134	57	31
Percentage of cycles resulting in live births ^b,c	63.3	60.4	46.3	38.6	19.4
Average number of embryos transferred	2.0	2.1	2.1	2.2	2.1

Donor Eggs

	All Ages Combined^e
	Fresh Embryos	Frozen Embryos
Number of transfers	204	93
Percentage of cycles resulting in live births ^b,c	70.6	53.8
Average number of embryos transferred	2.0	2.2

a) Reflects patient and treatment characteristics of ART cycles performed in 2009 using fresh, non-donor eggs or embryos
b) Pregnancies resulting in one or more children born alive (i.e., a multiple-infant birth is counted as one live birth).
c) When fewer than 20 cycles using fresh, non-donor eggs or embryos are reported in any one category, live birth rates are shown as fractions, and reliability ranges are not given. Calculation of percentage based on a fraction may be misleading and is not encouraged.
d) All ages (including age >42) are reported together because previous data show that patient age does not materially affect success with donor eggs.
e) For patients older than 42 undergoing ART cycles using fresh, non-donor eggs or embryos, clinic-specific outcome rates are unreliable. Patients are urged to review national outcomes for these age groups.

The above information was submitted to SART (Society for Reproductive Technology) in December, 2010 and has been included in the 2009 national report as well as the Centers for Disease Control and Prevention (CDC) 2009 ART statistics.

Research cycles are included in SART data, not in CDC data, thus you will notice a difference in the SART and CDC data reports.